While the residents of "Big Brother VIP Kosova" were discussing with each other about the uterus transplant, Edona James claimed that it is possible as a procedure and "her friend has given birth to a child". She did not specify whether or not her friend is a transgender woman, but considering that Edona herself is a transgender woman (born male, but identified as a woman) her statement was commented on the network as if it referred to the pregnancy of a transgender woman .

"He didn't do it [by birth] normally," she added, referring to the cesarean delivery. Edona's statement is unclear, although it most likely refers to the pregnancy of a cisgender woman whose gender identity (female) corresponds to her registered sex at birth (female). In the world, there have been several documented cases where (non-transgender) women with transplanted uteruses have become pregnant and given birth to children.

However, naturally one may ask: Is it possible for a transgender woman to become pregnant and give birth to a child? In theory, the procedure is not impossible, although difficult and dangerous.

When Mats Brännström – professor at the University of Gothenburg and head of the Department of Obstetrics and Gynaecology, Institute of Clinical Sciences in Sweden – first dreamed of performing a uterus transplant, he wanted to help women who were born without an organ or were undergoing operations to remove the uterus. His wish was to give them an opportunity to have children, especially in countries like Sweden where pregnancies through a surrogate mother are illegal.

Scientific American reports that he tried the procedure on female rodents, then moved on to sheep and baboons. He has performed uterus transplants on several non-transgender women and several babies have been born. His remarkable interventions increased the desire of transgender women to bear children.

The problem with the uterus transplant is extremely complex because it takes a lot of resources. First, the uterus, accompanying veins and arteries must be removed from a donor, which can be a living person or a cadaver. Then the organ must be placed in the person and see if it works, first by causing menstruation. If the patient has no further complications, doctors can implant an embryo through in vitro fertilization.

The baby must be delivered by caesarean section – as a precaution to avoid shock to the transplanted organ.

But for a transgender woman, even after changing the genital organ from the penis to the vagina, the process is much more difficult because she was born without the female reproductive system. Transgender women need a hormonal environment to nourish the uterus, along with the vagina.

Reproductive experts say that for these individuals, who are willing to take these steps, pregnancy is theoretically possible — but practically not easy.

The uterus transplant has been performed before. In one of the first medical efforts in the field, the transplant was performed by the Danish artist Lili Elbe (1882-1931). Lili (portrayed by actor Eddie Redmayne in the film "The Danish Girl"), hoping to have a child with her fiancé, underwent a uterus transplant in 1931 in Germany at the age of 48. Unfortunately, she developed a post-surgical infection and passed away from cardiac arrest three months later. Very little is known about the techniques the surgeons used, as the information was lost during World War II. Today, it is impossible to know whether the surgery could have resulted in a successful pregnancy.

Nowadays, pregnancy is possible for transgender men who have a functioning vagina, ovaries and uterus, but for transgender women, like Edona's case, further studies are still needed and no successful uterus transplants and pregnancies have been reported.

One way for a transgender woman to have biological children is to collect sperm and freeze the sperm before removing the genital organ (penis) so that they can be combined with someone else's egg in the future. At the moment, transgender women's pregnancy is uncharted territory.