Has it happened to you too? Feeling without energy, even though you have taken the "blessed" dose of daily coffee. A recent video of doctor Karan Raj shared on TikTok shows that this condition is not an illusion, but a fact that can happen to many people.
If caffeine makes you feel tired, this may be due to a "defect" in the fast or slow absorption of caffeine by your body or organism. CYP1A2, the enzyme he talks about in the video, is a metabolizing enzyme located in the liver. Several variants of this enzyme are known, some of them have an impact on the absorption of various medicines, and others on caffeine.
Depending on your metabolism, it can take anywhere from two to eight hours to get half of the caffeine. People with a mutation in the metabolism that absorbs caffeine more quickly cause the receptors of this liver enzyme to activate receptors that promote sleep, and this is why you feel more tired, even after coffee.
The doctor adds that if you drink a lot of coffee, your body simply reprograms itself, releasing even more enzymes of this nature, so that they don't give you that "awakening" and magical energy.
So the faster this liver enzyme is activated after coffee, the less energy you will feel!
Seems so unfair doesn't it!
Source: HuffPost
